Irreversible Electroporation: Implications for Prostate Ablation
نویسندگان
چکیده
منابع مشابه
Tumor Ablation with Irreversible Electroporation
We report the first successful use of irreversible electroporation for the minimally invasive treatment of aggressive cutaneous tumors implanted in mice. Irreversible electroporation is a newly developed non-thermal tissue ablation technique in which certain short duration electrical fields are used to permanently permeabilize the cell membrane, presumably through the formation of nanoscale def...
متن کاملIn vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation.
BACKGROUND Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are o...
متن کاملA Multi Objective Genetic Algorithm (MOGA) for Optimizing Thermal and Electrical Distribution in Tumor Ablation by Irreversible Electroporation
Background: Irreversible electroporation (IRE) is a novel tumor ablation technique. IRE is associated with high electrical fields and is often reported in conjunction with thermal damage caused by Joule heating. For good response to surgery it is crucial to produce minimum thermal damage in both tumoral and healthy tissues named Non-Thermal Irreversible Electroporation(NTIRE). Non-thermal irrev...
متن کاملA prospective development study investigating focal irreversible electroporation in men with localised prostate cancer: Nanoknife Electroporation Ablation Trial (NEAT)
INTRODUCTION Focal therapy may reduce the toxicity of current radical treatments while maintaining the oncological benefit. Irreversible electroporation (IRE) has been proposed to be tissue selective and so might have favourable characteristics compared to the currently used prostate ablative technologies. The aim of this trial is to determine the adverse events, genito-urinary side effects and...
متن کاملTissue heating during tumor ablation with irreversible electroporation
Exposing biological cells to sufficiently strong external electric fields causes electroporation of cell membranes, i.e. occurrence of transient or permanent permeable pathways between the interior and exterior of the cell. Electroporation can be used to introduce various molecules into cells (reversible electroporation) or to kill cells (irreversible electroporation), which can in turn be used...
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ژورنال
عنوان ژورنال: Technology in Cancer Research & Treatment
سال: 2007
ISSN: 1533-0346,1533-0338
DOI: 10.1177/153303460700600405